They are easy to grow, they bear very quickly. When you pick them from the cane and put them directly in your mouth they are much better than anything you can get from the grocery store or even farmer's market.

They are expensive to buy, fragile, and difficult to wash. I don't like soggy or squished raspberries, but I also don't like the idea of eating them unwashed relying on the cleanliness of the picker's hands and the treatment they've gotten after being picked.

If I had to name one fruit now to grow at home, it would be peaches, because although apples can be stored longer, are versitile, and are a wonderful fruit, I can buy very good apples at the supermarket, fruit stand, local orchard, etc. I can't buy decent peaches anywhere local.

As to original question; Honey Royale nectarine in the greenhouse and Eureka persimmon outdoors. The nectarine tastes the best but the persimmon is more reliable outdoors.

Fruitnut, Eureka would not survive outdoors zone 5 without a lot of protection

If I were to grow only one fruit, it wouldn't be the easiest care fruit for me, but the fruit which tasted the best home grown.

Peaches would be near the top. Home grown tomatoes are a close second.

And you just can't get good fresh apricots from the store, unlike with many other fruits.

I was planning to put in my favorite raspberries, Amity, at my place but maybe I should switch to just an early one instead of everbearing.

My vote would be for a hardy kiwi (actinidia arguta), very simply because they're so delicious. They're also very ornamental and could probably tolerate some shade if need be. They're virtually pest and disease free, but they require substantial work with trellising and pruning (but that's the kind of work I enjoy.) They seem to be reliable producers in some locations but very unreliable (if not reliably unproductive) in others (due presumably to frost damage, poor pollination, and/or difficult pruning), and I think that would be the greatest strike against them, although I'd still bet on hardy kiwis before I'd bet on something like no-spray peaches in northern Ohio.

I don't know if blueberries would be as easy to grow there as they are here, but if so blueberries would about be a tie. A northern highbush blueberry might be as easy as a rabbiteye is here, but North Carolina soils are probably more broadly suitable for blueberries than Ohio soils. Here blueberries are one of the easiest fruits to source from other good local sources, though. The best thing about blueberries here is just the combination of fruit quality and trouble-free productivity.

As has already been said, the versatility of apples (fresh eating, pies, applesauce, sweet cider, hard cider, cider vinegar...) and the potential to enjoy them over most of the year (with early and late and good storage varieties) makes a great argument for apples, although pest and disease difficulties (which may be a little lighter in northern Ohio than here) definitely detracts from their case, especially if you'd like a no-spray option.

I could also be happy (insofar as I could be happy with any one fruit) with a persimmon, either a native or an Asian hybrid like Rosseyanka. A persimmon is a very ornamental option, especially comparing it to other trees (as opposed to vines and bushes), and to me it's such a visually appealing fruit (even when others might think it looks half rotten as the ripe native fruits kind of do), and that visual appeal really adds to the enjoyment. I think it would be the easiest to grow and most adaptable fruit of the four I've mentioned.

If you had asked about my location, I might choose figs over all the others.

If i were to grow them here in zone 6 I would first try the MSU kiwi. Developed by MSU, well discovered on the tennis courts from what I understand. i went there, and have been on those tennis courts, before it was discovered, man I missed it! Although everything there is covered in vines. I left the Lansing area in 1987. MSU class of 81. I would think the MSU kiwi would grow fine here?