concerns of Tebuconazole-Resistant Isolates

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Posted by henry_kuska z5 OH (kuska@neo.rr.com) on

Mon, May 12, 14 at 16:40

There are concerns that azole type drugs are being overused. See for example:

https://www.google.com/url?q=http://www.rijksoverheid.nl/bestanden/documenten-en-publicaties/publicaties/2013/07/18/farm-fungicides-linked-to-resistance-in-a-human-pathogen/pg-106036d.pdf&sa=U&ei=bypxU6oylayxBImOgJAD&ved=0CBsQFjAA&usg=AFQjCNHjZy3ohT0J85TlleZE9pFIPHbtpw
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"And in a paper published in June, his group showed that resistant Aspergillus could be isolated from soil in flower beds close to hospitals and in commercial compost, leaves, and seeds bought at a garden center. Thirteen of 15 of these environmental samples also had the two mutations seen in clinical isolates."
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Specifically, does tebuconazole cause this type of mutation? Below is a very recent report that tebuconazole is no longer effective against a fungus strain that attacks wheat in New York.

http://apsjournals.apsnet.org/doi/abs/10.1094/PDIS-10-13-1051-RE

Here is a link that might be useful: Farm Fungicides Linked to Resistance in a Human Pathogen

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