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new tebuconazole full paper -human risk assessment

Posted by henry_kuska z5 OH (kuska@neo.rr.com) on
Tue, Aug 19, 14 at 20:27

The full paper is available free. I suggest reading the introduction, then using your browser's "Find" command using the keyword TEBU to see what it states about tebuconazole.
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"Our results show distinct in vitro anti-androgenic effects of several conazole fungicides arising from two mechanisms: inhibition of T secretion and AR antagonism, suggesting potential testicular toxic effects. These effects warrant further mechanistic investigation and clearly show the need for accurate exposure data in order to perform proper (human) risk assessment of this class of compounds

http://www.sciencedirect.com/science/article/pii/S2214750014000262

Here is a link that might be useful: link for above


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RE: new tebuconazole full paper -human risk assessment

  • Posted by seil z6b MI (My Page) on
    Mon, Aug 25, 14 at 14:53

I think it's pretty safe to assume no chemicals are good for us. Thanks, Henry!


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RE: new tebuconazole full paper -human risk assessment

For those who don't want to read on-- Many synthetic chemicals, including a number of pesticides, are probable "endocrine disruptors" that, typically, mimic female hormones or counteract male hormones. These, along with actual female hormones that are in our rivers downstream from cities (the consequence of using birth control pills), have the potential to keep developing male young from being fully masculinized. Probable evidence of these effects has been found in fish and frogs, which are particularly exposed owing to their spawning and developing in the water.

The paper Henry linked investigated ways that the conazole-type fungicides could disrupt hormones at the cellular level. They found that tebuconazole is likely an effective disruptor. Tebuconazole is the ingredient in Bayer Disease Control for Roses, Flowers, and Shrubs and some Bayer combo products. Women who are or might become pregnant should try to limit their exposure to endocrine disruptors.


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